In wireless communication, multiple input multiple output-orthogonal frequency division multiplexing (MIMO–OFDM) plays a major role because of its high transmission rate. A multiple-input multiple (MIMO) communication system combined with the orthogonal frequency division multiplexing (OFDM) modulation technique can achieve reliable high data rate transmission over broadband wireless channels. The channel estimation based on comb type pilot arrangement through different algorithms for estimating channel at pilot frequencies is investigated in this paper. The estimation of channel at pilot frequencies is based on LS, MMSE and LMMSE channel estimation algorithm. The performances of channel estimation algorithm is compared in LS, MMSE and LMMSE channel estimation techniques by measuring MSE vs. SNR with QPSK modulation scheme. LMMSE estimation has been shown to perform much better than LS and MMSE.